
Intro - Cell Cycle Control System (4.2)
Presentation
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Science
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12th Grade
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Practice Problem
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Easy
Standards-aligned
Lauren Cochrane
Used 1+ times
FREE Resource
21 Slides • 23 Questions
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Multiple Choice
Which of the following best describes the role of a checkpoint in the cell cycle?
It is a control point where stop and go-ahead signals regulate the cell cycle.
It is the location where cells divide rapidly.
It is the site where DNA is replicated.
It is the place where cells die.
4
Open Ended
Why is it important for the cell cycle to have a control system with checkpoints?
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6
Multiple Choice
Which of the following phases is NOT associated with a major cell cycle checkpoint?
G1 phase
S phase
G2 phase
M phase
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Open Ended
Explain the role of checkpoints in the cell cycle and why they are crucial for cellular health.
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10
Fill in the Blanks
Type answer...
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Open Ended
Describe how non-dividing cells, such as mature nerve cells, differ from liver cells in terms of their ability to re-enter the cell cycle.
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14
Multiple Choice
Which condition is NOT checked by the G1 checkpoint before allowing a cell to continue through the cell cycle?
Adequate cell size
Presence of growth factors
Proper chromosome alignment
No damage to DNA
15
Multiple Select
Select all statements that correctly describe the G1 checkpoint.
It checks for DNA damage.
It ensures the cell has grown to an adequate size.
It checks for proper chromosome alignment.
It verifies the presence of growth signals and nutrients.
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Multiple Choice
Which checkpoint ensures that all kinetochores are properly attached to microtubules before the cell proceeds to anaphase?
G1 checkpoint
G2 checkpoint
M checkpoint
S checkpoint
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Multiple Select
Which of the following statements about cyclins and CDKs is/are correct?
CDKs are only activated when bound to cyclins.
Cyclins are enzymes that phosphorylate other proteins.
Cyclin-CDK complexes allow cells to pass each checkpoint.
CDKs are destroyed after activating target proteins.
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Open Ended
Explain the role of cyclin-dependent kinases (CDKs) in the regulation of the cell cycle.
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24
Multiple Choice
During which phase of the cell cycle does Cyclin E reach its highest concentration?
G1 Phase
S Phase
G2 Phase
Mitosis
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Fill in the Blanks
Type answer...
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Open Ended
Compare the effect of the presence and absence of G1/S cyclin on the activity of Cdk and the initiation of S phase.
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Multiple Choice
Which process stops cell division when cells become too crowded at the G1 checkpoint?
Density-dependent inhibition
Apoptosis
Cell differentiation
Mitosis
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Open Ended
Explain how the G2 checkpoint regulates cell division through both stimulation and inhibition mechanisms.
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Multiple Select
Which of the following are possible fates of a cell after receiving specific molecular signals?
Mitosis and division
Differentiation
Apoptosis
Mutation
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Fill in the Blanks
Type answer...
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39
Fill in the Blanks
Type answer...
40
Open Ended
What are the two types of genes that regulate the cell cycle and how do mutations in these genes contribute to cancer?
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Multiple Choice
Which of the following best explains how mutations in proto-oncogenes and tumor suppressor genes can lead to cancer, as illustrated in the diagram?
Mutations cause proto-oncogenes to become oncogenes, resulting in too much cell growth (too much gas), and inactivation of tumor suppressor genes removes growth inhibition (no brake), both leading to cancer.
Mutations in proto-oncogenes slow down cell growth, while tumor suppressor genes speed it up, preventing cancer.
Proto-oncogenes and tumor suppressor genes have no effect on cell growth or cancer development.
Mutations in tumor suppressor genes increase the braking effect, stopping cell growth completely.
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Open Ended
How do internal and external signals influence the regulation of the cell cycle control system?
44
Multiple Choice
What is the role of a checkpoint in the cell cycle control system?
It acts as a control point for stop and go-ahead signals.
It initiates cell division in all cell types.
It prevents any cell from dividing.
It only responds to external signals.
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