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Untitled Presentation

Untitled Presentation

Assessment

Presentation

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Hospitality and Catering

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University

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Hard

Created by

jingo haluhu

Used 1+ times

FREE Resource

29 Slides • 21 Questions

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Multiple Choice

Which of the following best describes a live-attenuated vaccine?

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A vaccine made from inactivated viruses

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A vaccine made from weakened but live viruses

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A vaccine made from only parts of the virus, such as proteins

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A vaccine made from toxins produced by bacteria

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Open Ended

What is the significance of using different types of vaccines, such as live-attenuated and viral-like particle vaccines, in immunization programs?

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Multiple Choice

What is the main reason for the efficiency of IgM in binding antigens during a primary infection?

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Formed without antigen stimulation

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Very high affinity

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Has 10 antigen binding sites

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Not affected by extreme pH

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Binds antigen covalently

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Multiple Choice

What is the primary function of the Western Blot technique in HIV testing?

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Assess antibody avidity

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Determine immunoglobulin class

3

Confirm specific antibody to a certain protein

4

Measure viral antigen levels

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Multiple Choice

What is the main advantage of the RIA method for thyroid hormone detection?

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Does not require antibodies

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Does not require a reader device

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Can detect antigen at very low concentrations

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Does not use radioactive materials

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Multiple Choice

What conclusion can be drawn if an Ag-Ab complex dissociates when the pH is drastically lowered?

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Ag-Ab bond is covalent

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Complex cannot be decomposed by temperature

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Complex can be broken by changes in pH or ionic strength

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Binding only involves hydrophobic interactions

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Multiple Choice

A woman receives a Hepatitis B vaccine containing only viral surface protein and requires a booster due to low immunogenicity. What type of vaccine is this?

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DNA vaccine

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Toxoid

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Subunit vaccine

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Live-attenuated

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Open Ended

Explain why antigen-antibody reactions are not optimal at pH 4 and the antibody loses its ability to bind antigen.

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Multiple Choice

A 45-year-old man receives a rabies vaccine derived from a virus that has been inactivated so it cannot replicate, but requires several booster doses. What type of vaccine is this?

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Viral-like particle vaccine

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Inactivated/killed vaccine

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DNA vaccine

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Live-attenuated

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Toxoid vaccine

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Multiple Choice

A 9-month-old boy is brought to the clinic for measles immunization. The doctor explains that the vaccine works by mimicking natural infection because the virus used is still alive but has been weakened so it cannot cause disease. This vaccine stimulates long-term immunity. What type of vaccine is this?

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Toxoid

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Live-attenuated vaccine

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Subunit vaccine

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Inactivated vaccine

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Viral-like particle

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Multiple Choice

A 22-year-old female comes for HPV vaccination. This vaccine contains a capsid protein structure resembling a virus but without DNA, making it safe to use. What type of vaccine is this?

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Viral-like particle vaccine

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Live-attenuated vaccine

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Toxoid vaccine

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DNA vaccine

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mRNA vaccine

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Multiple Choice

A 32-year-old woman with SLE is taking immunosuppressants and wants to receive the influenza vaccine. The doctor explains that the vaccine response may be suboptimal because the medication suppresses B and T lymphocyte proliferation. What is the main mechanism?

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Influenza vaccine is a live vaccine

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Patient's antibodies undergo cross-reactivity

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Immunosuppressant drugs reduce the body's ability to produce antibodies

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Vaccine cannot activate complement

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Patient previously received passive immunization

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Multiple Choice

A student conducts an ELISA test for anti-HIV antibodies. After adding the substrate, a color change occurs, indicating enzyme activity in the antigen-antibody complex. What is the mechanism involved?

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Enzyme-substrate reaction in the Ag-Ab complex

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Agglutination of particulate antigen

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Complement activation

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Covalent binding of antigen-antibody

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Antigen denaturation

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Multiple Choice

A 27-year-old man is bitten by a snake and given antivenom. His symptoms improve quickly, but the doctor explains that the protection does not last long and does not form immune memory. What type of immunization is this?

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Live virus vaccine

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Active immunization

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Subunit vaccine

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Passive immunization

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DNA vaccine

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Multiple Choice

A 5-year-old child receives a tetanus vaccine made from inactivated Clostridium tetani toxin. What type of vaccine is this?

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Subunit vaccine

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Viral vector

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Toxoid

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Inactivated whole virus

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Multiple Choice

The Widal test shows clumping when antigen is mixed with patient serum. What reaction is occurring?

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Toxin neutralization

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Complement fixation

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Immobilization

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Agglutination

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Multiple Choice

A researcher wants to measure the strength of a single antibody paratope binding to a single antigen epitope. What parameter is being measured?

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Avidity

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Affinity

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Valency

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Opsonization

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Multiple Choice

IgM increases in primary infection and can efficiently bind antigens due to having many binding sites. What is the reason for this efficiency?

1

Formed without antigen stimulation

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Very high affinity

3

Has 10 antigen binding sites

4

Binds antigen covalently

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Multiple Choice

What is the main function of the Western Blot in HIV testing?

1

Assess antibody avidity

2

Determine immunoglobulin class

3

Confirm specific antibody to a certain protein

4

Detect antigen in small amounts

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Multiple Choice

A patient undergoes RIA for thyroid hormone. This method is very sensitive because it uses radioisotopes to detect very small amounts of antigen. What is the main advantage of this method?

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Does not require antibodies

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Does not require a reader device

3

Can detect antigen at very low concentrations

4

Does not use radioactive material

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Open Ended

After learning about different types of vaccines, what questions do you still have or what would you like to know more about?

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