13.1-13.2
Presentation
•
Biology
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10th Grade - University
•
Hard
Nikki Chenevert
FREE Resource
95 Slides • 12 Questions
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by Nikki Chenevert
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Chapter 13: The Molecular Basis of Inheritance
Outline:
Life’s Operating Instructions
Deoxyribonucleic Acid, DNA, the genetic material/substance of inheritance of all living organisms
DNA Replication
13.1 DNA is the genetic material
The Search for the Genetic Material: Scientific Inquiry
Genes or proteins, which is the genetic material?
Evidence that DNA Can Transform Bacteria
Griffith’s Transformation (Figure 13.3)
i. R strain pneumonia is harmless, Mice + R = healthy
ii. S strain pneumonia is pathogenic (disease causing), Mice + S = death
iii. Mice + live R + heat killed S = death
iv. Transformation of R strain to S strain, the genetic material from S strain was inherited by descendants
v. Explanation: S strain had been killed, but its genetic information (the component that made it lethal) was still intact.
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Multiple Choice
Who gets credit (wins the Nobel Prize) for elucidating the structure of DNA?
Griffith
Gregor Mendel
Avery, MacLeod, and McCarty
Franklin and Wilkins
Watson and Crick
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Multiple Choice
Hershey and Chase used radioactive labels for the DNA (P) and proteins (S) of bacteriophage viruses. Their experiment shows that ________ carries the genetic material of bacteriophage viruses, because the radioactive _____ was found inside of infected bacteria.
DNA; radioactive phosphorus
Proteins; radioactive sulfur
Proteins and DNA; both phosphorus and sulfur
RNA; Neither phosphorous nor sulfur
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Multiple Choice
Which scientist(s) work indicated that DNA has a helical shape?
Select one:
Chargaff
Hershey and Chase
Franklin and Wilkins
Watson and Crick
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Multiple Choice
Rosalind Franklin used which technique to determine many of the physical characteristics of DNA?
Density-gradient centrifugation
Transmission electron microscopy
Transformation
X-ray diffraction
Phage experiments
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Multiple Choice
_______ seals the nicks in the DNA backbone left by synthesis of Okazaki fragments.
DNA polymerase II
Single strand binding (ssb) proteins
Ligase
DNA polymerase I
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Multiple Choice
Which of the following enzymes unwinds the DNA double helix for replication?
RNA polymerase
DNA polymerase
DNA Helicase
Topoisomerase
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Multiple Choice
The enzyme _______ prevents supercoiling of DNA by relieving torque.
DNA polymerase II
Single strand binding (ssb) proteins
Ligase
Helicase
Topoisomerase (Gynase)
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Multiple Choice
______ replaces the RNA primer and fills the gaps with DNA.
DNA polymerase II
Single strand binding (ssb) proteins
Ligase
DNA polymerase I
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Multiple Choice
New nucleotides are added in a complementary fashion by_________
DNA polymerase II
Helicase
DNA polymerase I
Topoisomerase (Gynase)
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Multiple Choice
The enzyme ______ opens the DNA double helix using ATP.
Ligase
Helicase
DNA polymerase I
Topoisomerase (Gynase)
DNA polymerase II
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Multiple Choice
Transcription produces a _________ molecule from a ___________ template.
Polypeptide; RNA
DNA; DNA
RNA, DNA
DNA; RNA
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Multiple Choice
Translation produces a ______ molecule from a ______ template.
RNA; DNA
DNA; RNA
Polypeptide; RNA
DNA; DNA
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