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Xenobiotics and Metabolism Quiz

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Xenobiotics and Metabolism Quiz
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20 questions

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1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following best defines xenobiotics?

Essential nutrients

Foreign compounds in the body

Vitamins

Endogenous metabolites

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which organ is primarily responsible for xenobiotic metabolism?

Kidney

Liver

Lung

Skin

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which enzyme system plays a major role in Phase I reactions?

Alcohol dehydrogenase

Cytochrome P450

Glutathione peroxidase

Superoxide dismutase

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Phase I reactions in xenobiotic metabolism include?

Conjugation

Hydrolysis

Acetylation

Glucuronidation

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following is a Phase II reaction?

Oxidation

Hydroxylation

Glucuronidation

Reduction

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the main purpose of Phase II reactions?

Detoxify by oxidation

Make xenobiotics more lipid soluble

Make xenobiotics more water soluble

Activate prodrugs

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which cofactor is required for glucuronidation?

PAPS

UDP-glucuronic acid

Acetyl-CoA

NADPH

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