Enzymes and Nucleotide Disorders Quiz
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20 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which enzyme is deficient in Lesch-Nyhan syndrome?
HGPRT
PRPP synthetase
ADA
AMP deaminase
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the end product of purine catabolism in humans?
Urea
Uric acid
Allantoin
Creatinine
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
De novo synthesis of pyrimidines begins with which of the following?
Ribose-5-phosphate
Carbamoyl phosphate
PRPP
Orotate
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Allopurinol is used in the treatment of which condition?
Orotic aciduria
Gout
SCID
Phenylketonuria
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which of the following is NOT associated with primary gout?
HGPRT deficiency
PRPP synthetase overactivity
Renal failure
Increased purine synthesis
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which intermediate accumulates in Orotic aciduria?
Uric acid
Orotate
Inosine
Orotidine
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Purine salvage pathway utilizes which of the following enzymes?
Xanthine oxidase
PRPP synthetase
Hypoxanthine-guanine phosphoribosyltransferase (HGPRT)
CPS II
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