Quiz2_QSAR
Authored by Sumana Chatterjee
Chemistry
University
Used 34+ times
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10 questions
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1.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
What does the symbol P represent in a QSAR equation?
pH
Partition coefficient
Plasma concentration
Prodrug
2.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
What is the symbol π in a QSAR equation?
The hydrophobicity of the molecule
The electronic effect of a substituent
The substituent hydrophobicity constant
A measure of the steric properties for a substituent
3.
MULTIPLE CHOICE QUESTION
2 mins • 1 pt
Calculate the logP value of p- Hydroxy toluene if logP for benzene = 2.13; π(OH) -0.67; π(CH3) 0.52.
3.32
0.94
1.98
2.13
4.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
What does MR represent in a QSAR equation?
Molar refractivity is a steric factor
Molar refractivity is an electronic factor
Molar refractivity is a hydrophobic factor
Molar refractivity is a stereoelectronic factor
5.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
What software programme is used to determine the Verloop steric parameter?
Alchemy
Chem3D
Sterimol
ChemDraw
6.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
What does a positive value of σ signify for a substituent?
It is electron donating
It is electron withdrawing
It is neutral
t is hydrophobic
7.
MULTIPLE CHOICE QUESTION
45 sec • 1 pt
A negative π value indicates
higher lipophilicity
lower lipophilicity
electron with drawing group
electron donating group
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