

Mitosis + checkpoints
Presentation
•
Biology
•
12th Grade
•
Practice Problem
•
Medium
Standards-aligned
Christine Collins
Used 1+ times
FREE Resource
30 Slides • 19 Questions
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Multiple Choice
During which phase of mitosis do microtubules begin attach to kinetochores?
Prometaphase
Metaphase
Anaphase
Telophase
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7
Multiple Select
Which of the following events occur during metaphase?
Chromosomes line up at the metaphase plate
Centrosomes are at opposite poles
Microtubules are attached to each kinetochore
Nuclear envelope fragments
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9
Multiple Choice
Which of the following accurately describes what happens during anaphase?
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12
Multiple Choice
Which of the follow is NOT a characteristics of telophase and cytokenesis?
One parent cell finishes separating into two daughter cells
13
Multiple Choice
Which of the following accurately lists the phases of mitosis in order?
Anaphase, Prophase, Telophase,
Cytokenesis
Interphase
Prophase,
Prometaphase,
Metaphase, Anaphase, Telophase,
Cytokenesis
Prophase, Anaphase, Telophase,
Interphase
Cytokinesis
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17
Multiple Choice
What is the chromosome number in each daughter cell after mitosis if the parent cell is 2n=2?
2
4
1
8
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Multiple Choice
Movement of the chromosomes during anaphase would be most affected by a drug that prevents:
Nuclear envelope breakdown
Cell wall formation
elongation of microtubules
Shortening of microtubules
Formation of a cleavage furrow
21
Multiple Choice
Eukaryotic chromatin is composed of
Condensed DNA only
DNA and RNA
DNA and Carbohydrates
DNA and Protein
DNA and Ribosomes
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Multiple Choice
If a sperm cell contains 12 chromosomes, it comes from an animal that has ___ chromosomes
4
8
12
16
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Open Ended
A cell has 50 chromosomes. After mitosis and cell division, you find that one daughter cell has 49 chromosomes and the other daughter cell has 51 chromosomes. Predict one way that this could have happened.
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Multiple Choice
When in cell life does the G1 checkpoint occur?
At the end of interphase
During telophase
During Anaphase
At the end of the G1 phase of interphase.
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Multiple Choice
Are cells in G0 dividing?
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Multiple Select
Which of the following are true about the G2 checkpoint?
It checks for completion of DNA replication.
It checks for DNA damage.
It allows the cell to proceed to mitosis if conditions are met.
It checks for microtubule attachment to chromosomes.
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34
Multiple Choice
Which of the following statements about cyclins is correct?
Cyclin concentration varies during the cell cycle.
Cyclins are only synthesized during mitosis.
Cyclins are never degraded.
Cyclins are enzymes.
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Multiple Choice
Which cyclin is most abundant during the G1 phase of the cell cycle?
Cyclin D
Cyclin E
Cyclin A
Cyclin B
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Growth Factor
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Anchorage dependence
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Fill in the Blanks
Type answer...
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Multiple Choice
Which of the following is NOT a characteristic of cancer cells compared to normal cells?
They follow checkpoints
They divide infinitely in culture
They evade apoptosis
They are considered 'immortal'
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Open Ended
Explain the difference between benign and malignant tumors, and describe the process of metastasis.
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Open Ended
Vinblastine is a chemotherapeutic drug often administered to patients suffering from Hodgkin’s lymphoma, lung cancer, and bladder cancer. Vinblastine works by entering cancer cells and binding to tubulin, which is a protein that forms microtubules. Once Vinblastine has bound to tubulin, it inhibits the assembly of microtubules and proper formation of the mitotic spindle. This causes the cell cycle to arrest. a) Identify and explain two phases of the cell cycle most affected by Vinblastine. b) Identify the checkpoint that is most likely responsible for arresting the cell cycle.
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