Week 14: Mutation Evaluation

Presentation

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Science

•

9th Grade

•

Practice Problem

•

Medium

•

NGSS

HS-LS3-2, HS-LS1-1, HS-LS4-2

Standards-aligned

Alicia Tamayo

Used 11+ times

FREE Resource

3 Slides • 24 Questions

Mutation Evaluation!

Match

Match the following base pairs used during replication (DNA->DNA)

Thymine (T)

Cytosine (C)

Adenine (A)

Guanine (G)

Adenine (A)

Guanine (G)

Thymine (T)

Cytosine (C)

Match

Match the following base pairs used during transcription (DNA->RNA).

Adenine (A)

Thymine (T)

Cytosine (C)

Guanine (G)

Uracil (U)

Adenine (A)

Guanine (G)

Cytosine (C)

Multiple Choice

A mutation is defined as

A temporary change in an organism's environment.

A process of natural selection in evolution.

A change in the DNA sequence of an organism.

A random alteration in an organism's physical traits.

Multiple Choice

If a mutation occurs in an expressed gene, it will most directly affect the structure of a cell's

nucleic acids

carbohydrates

lipids

proteins

Match

Identify the correct point/gene mutation with its description.

Insertion

Deletion

Substitution - Missense

Substitution - Silent

Substitution - Nonsense

A nucleotide is added

A nucleotide is removed

A single amino acid changes

No change in amino acid sequence

An amino acid changes to STOP

Hotspot

Identify where the difference in the DNA sequences is

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

Multiple Choice

Identify the type of mutation.

Substitution - Silent

Substitution - Missense

Substitution - Nonsense

Insertion

Deletion

The next part is 6 questions where you will do each step in determining the type of mutation!

These are the steps you should follow each time when given a mutated DNA sequence.
Remember: You always have to compare to the orginal!

Fill in the Blanks

Part 1: Transcribe the Original DNA Sequence: ATG CGA CCA

Fill in the Blanks

Original DNA: ATG CGA CCA

Original RNA: UAC GCU GGU

Part 2: Translate the Original DNA sequence.

Fill in the Blanks

Original DNA: ATG CGA CCA

RNA: UAC GCU GGU

Amino Acids: Tyr Ala Gly

Mutated DNA: ACG CGA CCA

Part 3: Transcribe the Mutated DNA sequence.

Fill in the Blanks

Original DNA: ATG CGA CCA

Original RNA: UAC GCU GGU

Original Amino Acids: Tyr Ala Gly

Mutated DNA: ACG CGA CCA

Mutated RNA: UGC GCU GGU

Part 4: Translate the Mutated RNA sequence.

Multiple Choice

Original DNA: ATG CGA CCA

Original RNA: UAC GCU GGU

Original Amino Acids: Tyr Ala Gly

Mutated DNA: ACG CGA CCA

Mutated RNA: UGC GCU GGU

Mutated Amino Acids: Cys Ala Gly

Part 5: Identify the Type of mutation that occurred.

Deletion

Insertion

Substitution - Missense

Substitution - Nonsense

Substitution - Silent

Congratulations!

I can IDENTIFY they type of gene mutation and its effect on the amino acid sequence (protein chain)
I can transcribe and translate and analyze the type of mutation and its effect on the amino acid sequence

Poll

How confident are you on these two learning targets?

I can IDENTIFY they type of gene mutation and its effect on the amino acid sequence (protein chain)

I can transcribe and translate and analyze the type of mutation and its effect on the amino acid sequence

Not confident at all

Somewhat confident

Very confident

Mutation Evaluation!

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