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Cell Signal

Cell Signal

Assessment

Presentation

Science

9th - 12th Grade

Hard

NGSS
HS-LS1-3

Standards-aligned

Created by

Joseph Anderson

FREE Resource

7 Slides • 16 Questions

1

Cell Signaling Check-In

2

All signaling systems generally have ligands, receptors, and the three stages of reception, transduction, and response. The differences in the systems are illustrated through signaling diagrams.

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3

Fill in the Blanks

4

Fill in the Blanks

5

Reorder

Reorder the following from beginning to finish

Reception

Transduction

Response

1
2
3

6

Categorize

Options (12)

within cytoplasm

ligand binds complementary receptor

can happen at membrane or within cytoplasm

message is passed along and often amplified

cell may produce a protein

cell may stop producing a protein

cell may move

cell may die

cell may grow and divide

multiple proteins will change shape

any ligand binds any receptor

happens only at membrane

Organize the events and locations within the stages of cellular signaling.

Reception
Transduction
Response
N/A, False

7

Hotspot

For each example, IDENTIFY the receptor(s).

8

Hotspot

For each example, IDENTIFY the receptors.

9

Like respiration, this could be worse.

On the next page you will see an interactive that shows what a cell's membrane-area looks like in actuality.

Suggested pathways to select using the upper lefthand corner
Endocytosis
Insulin Receptor Signaling

Click at least one protein and see how much information has been documented. Scan for words you are familiar with!

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​A person can get a PhD just studying one section of one of these pathways. I'm not kidding. Here's the notification I got the other day from a school I did research at.

10

11

Match

Match the following, assuming we are discussing cell signaling and not chemical reactions.

Not Pictured

A activates or increases B

G inhibits or decreases H

Reactant A is converted to product B

12

We will convert phrases into arrow notation.

13

Dropdown

X activates Y

​ ​ ​

14

Dropdown

P inhibits Q

​ ​
​ ​

15

Dropdown

R is inhibited by M

​ ​

16

Dropdown

D is decreased because of C

17

Dropdown

Write a sentence describing this pathway



Adrenaline → Receptor A → Heart rate



Adrenaline
Receptor A which ​
heart rate.

18

Open Ended

Write a sentence describing this pathway.

Acetylcholine → Receptor B --| Heart rate

sa dsf

19

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For multi-step pathways, simplify the into the overall result

Understanding pathway diagrams

20

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Just like math class, a negative times a negative = a positive

Inhibition x inhibition = activation

21

Multiple Choice

Question image

The overall result of this pathway is that...

1

J inhibits M

2

J activates M

3

J inhibits L

4

J inhibits K

22

Draw

Annotate the diagram to show the individual effects of low oxygen on erythrocytes.

23

Open Ended

Question image

PREDICT the effects on erythropoietin secretion if you moved from Denver (low oxygen) to San Diego (high oxygen).

JUSTIFY your answer.

Cell Signaling Check-In

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