

Cell Signal
Presentation
•
Science
•
9th - 12th Grade
•
Hard
Standards-aligned
Joseph Anderson
FREE Resource
7 Slides • 16 Questions
1
Cell Signaling Check-In
2
All signaling systems generally have ligands, receptors, and the three stages of reception, transduction, and response. The differences in the systems are illustrated through signaling diagrams.
3
Fill in the Blanks
4
Fill in the Blanks
5
Reorder
Reorder the following from beginning to finish
Reception
Transduction
Response
6
Categorize
within cytoplasm
ligand binds complementary receptor
can happen at membrane or within cytoplasm
message is passed along and often amplified
cell may produce a protein
cell may stop producing a protein
cell may move
cell may die
cell may grow and divide
multiple proteins will change shape
any ligand binds any receptor
happens only at membrane
Organize the events and locations within the stages of cellular signaling.
7
Hotspot
For each example, IDENTIFY the receptor(s).
8
Hotspot
For each example, IDENTIFY the receptors.
9
Like respiration, this could be worse.
On the next page you will see an interactive that shows what a cell's membrane-area looks like in actuality.
Suggested pathways to select using the upper lefthand corner
Endocytosis
Insulin Receptor Signaling
Click at least one protein and see how much information has been documented. Scan for words you are familiar with!
A person can get a PhD just studying one section of one of these pathways. I'm not kidding. Here's the notification I got the other day from a school I did research at.
10
11
Match
Match the following, assuming we are discussing cell signaling and not chemical reactions.
Not Pictured
A activates or increases B
G inhibits or decreases H
Reactant A is converted to product B
A activates or increases B
G inhibits or decreases H
Reactant A is converted to product B
12
We will convert phrases into arrow notation.
13
Dropdown
14
Dropdown
15
Dropdown
16
Dropdown
17
Dropdown
Adrenaline → Receptor A → Heart rate
Adrenaline
18
Open Ended
Write a sentence describing this pathway.
Acetylcholine → Receptor B --| Heart rate
sa dsf
19
For multi-step pathways, simplify the into the overall result
Understanding pathway diagrams
20
Just like math class, a negative times a negative = a positive
Inhibition x inhibition = activation
21
Multiple Choice
The overall result of this pathway is that...
J inhibits M
J activates M
J inhibits L
J inhibits K
22
Draw
Annotate the diagram to show the individual effects of low oxygen on erythrocytes.
23
Open Ended
PREDICT the effects on erythropoietin secretion if you moved from Denver (low oxygen) to San Diego (high oxygen).
JUSTIFY your answer.
Cell Signaling Check-In
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