Buildup of IgE on mast cells

Activation of complement

Increase in cytotoxic T cells

Large amount of circulating IgG

Chemotaxis of neutrophils

Hemolysis

Release of preformed mediators

Deposition of immune complexes

Production of IgE in response to allergen

Deposition of immune complexes occurs

Cytotoxic reaction involving IgG and/or IgM

Sensitized T cells produce delayed cell mediated response

Type I

Type II

Type III

Type IV

Involvement of antibody

Asymptomatic sensitization phase

Release of histamine

Activation of macrophages against a pathogen

Leukotriene

Prostaglandin

Histamine

Platelet Activating Factor (PAF)

Buildup of IgE on mother's cells

Sensitization of cytotoxic T cells

Exposure to antigens found on both mother and baby red cells

Prior exposure of mother to foreign red cell antigen

Attracts eosinophils to the area

Contraction of smooth muscle in bronchioles and intestines

Causes platelet aggregation

Attracts neutrophils to the area

Type IV

Type III

Type II

Type I

CD2, CD3, CD8

HLA-C

HLA-DR

HLA-Q

Deletion of self reactive T cells

No change to self antigens after exposure to radiation

Bacteria with antigens that are very different from self antigens

Failure to delete self reactive B cells

Tumor specific antigens

Virus induced tumor antigens

Genome encoded tumor antigens

Oncofetal antigens

Mature cells

Disorganized behaviour

Immature cells

An uncontrolled growth of abnormal cells

Tumor Specific Antigen

Virus Induced Tumor Antigen

Genome Encoded Tumor Antigen

Oncofetal Antigen

Present at birth

Hereditary immunodeficiency

Acquired after birth

Defect in development of immune system

True

False

Hereditary Angiodema

Wiskott-Aldrich Syndrome

Selective IgA Deficiency

Nezelof's Syndrome