The Effects of Mutation

Protein X is going to be represented by this code: Methionine—Phenylalanine—Tryptophan—Asparagine—Isoleucine—STOP.

1. Use the genetic code table to determine one possible sequence of RNA (codons) to code for this information.

2. Write the DNA code (pairing DNA) that would produce this RNA sequence.

1. Now, cause a mutation in the gene sequence that you just determined by deleting the fourth base (4th letter) in the DNA sequence.

2. Write this new DNA sequence, this will be fProtein Y.

1. Write the new RNA sequence that would be produced from DNA sequence on the previous slide.

2. Write the amino acid sequence that would result from this mutation in your gene, which will be called Protein Y.

Did this single deletion of the 4th base cause much change in your protein?

Explain your answer.