6.5C&D

Release of cholinesterase into the synaptic cleft

Increased re-uptake of dopamine and serotonin by presynaptic neurons

Increased permeability of the presynaptic neuron to sodium

Blockage of dopamine and serotonin receptors on presynaptic neurons

Depolarization

Repolarization

Resting potential

Hyperpolarization

I only

I and II only

I and III only

I, II and III

It prevents the release of acetylcholine from the presynaptic membrane.

It widens the synaptic cleft so diffusion of acetylcholine across the gap is slower.

It irreversibly binds with acetylcholine receptors on the postsynaptic membrane.

It interferes with the enzymatic breakdown of acetylcholine by acetylcholinesterase.

Transmission of the nerve impulse in the presynaptic neuron

Formation of the synaptic vesicles

Release of the neurotransmitter

Binding of neurotransmitters to postsynaptic acetylcholine receptors