KA6a Gene Mutations

What type of point mutation is this?

Sickle cell anaemia is a human condition that affects haemoglobin, reducing the blood’s ability to carry oxygen.

It is caused by a mutation that changes one adenine base to thymine. This results in one amino acid in haemoglobin being changed.

The mutation that causes sickle cell anaemia is

Normal-

AGA-TTC-ATA-GCG

Mutant-

AGA-TTC-AAT-AGC-G

An original DNA segment is TTACGCAAG

Mutated DNA segment is TTCGCAAG.

This is an example of ___ mutation.