
Drug Development
Presentation
•
Science
•
9th - 11th Grade
•
Medium
Michelle Grant
Used 5+ times
FREE Resource
11 Slides • 10 Questions
1
Drug Development
Justify the stages in drug testing
*Recall the stages in drug testing
*Describe potential new sources of medicines
*Relate the stages in drug testing to the 4 properties of a successful medicine
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3
Key questions to answer:
1) Does it work? ** effective**
2) Is it safe? **side effects/toxic?**
3) How much do I need? ** Dosage**
4) How do I store it? ** Chemically stable**
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Developing Drugs
Chemical analysis of drug
Pre clinical trials: Test on cells & animals
Clinical trials: Test on a small number of healthy volunteers (double blind trials)
Test on a small number of volunteers with the illness (double blind trials)
Test on a large number of volunteers with the illness (double blind trials)
Peer review findings
Continue to monitor when drug is liscenced
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Multiple Choice
Why are drugs tested on animals?
It is cheap and easy to do
It checks for side effects
To see if they are suitable as cosmetics
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Multiple Choice
In which sort of trial do the researchers know which group the volunteers are in, but the volunteers do not?
Blind trial
Double Blind Trial
Open Trial
10
Multiple Choice
Why do scientists grow bacteria in the laboratory?
To allow them to check the effectiveness of antibiotics or antibacterial substances at killing them
To be able to calculate the number of bacteria in a population.
To allow infectious diseases to be cultured.
11
Multiple Choice
How are drugs checked for safety?
Drugs are tested for efficacy, toxicity and dosage
By giving them to humans first
By giving people a placebo
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Multiple Choice
What are the different stages of drugs trials?
Testing it on humans to see if the side effects are harmful
On human volunteers first and then on animals
Preclinical trials using cells, tissues and animals. Then clinical trials using healthy human volunteers and patients.
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Multiple Choice
Which drug was originally isolated from willow bark?
Paracetamol
Aspirin
Digitalis
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Multiple Choice
What is a placebo?
An inactive substance used as a control in clinical trials
A concentrated form of a drug used in clinical trials
A type of injection using very fine needles
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Multiple Choice
How do antibiotics work?
They can stop bacteria from growing or reproducing
They can stop viruses from growing or reproducing
They can stop toxins poisoning the tissues of the host
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Multiple Choice
How do vaccines work?
A weakened/inactive version of a virus is injected to stimulate antibody production
They can stop viruses from growing or reproducing by producing antitoxins
A weakened/inactive version of a virus is injected to stimulate antigen production
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Multiple Choice
Which of following describes how antibodies are released after a person has been vaccinated?
Quickly and in large amounts
Slowly but in large amounts
The same as before
Quickly but a different antibody is made
21
Drug Development
Justify the stages in drug testing
*Recall the stages in drug testing
*Describe potential new sources of medicines
*Relate the stages in drug testing to the 4 properties of a successful medicine
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